Fred H. Gage, PhD

[Talk Title]

[Bio]

Reading List 

Herdy, Joseph R., Jerome Mertens, et al. “Neuronal senescence may drive brain aging.” Science, vol. 384, no. 6703, 28 June 2024, pp. 1404–1406, https://doi.org/10.1126/science.adi3450.

Herdy, Joseph R., Larissa Traxler, et al. “Increased post-mitotic senescence in aged human neurons is a pathological feature of alzheimer’s disease.” Cell Stem Cell, vol. 29, no. 12, Dec. 2022, https://doi.org/10.1016/j.stem.2022.11.010.

Mertens, Jerome, et al. “Age-dependent instability of mature neuronal fate in induced neurons from alzheimer’s patients.” Cell Stem Cell, vol. 28, no. 9, Sept. 2021, https://doi.org/10.1016/j.stem.2021.04.004.

Parylak, Sarah L., et al. “Neuronal activity‐related transcription is blunted in immature compared to mature dentate granule cells.” Hippocampus, vol. 33, no. 4, 22 Feb. 2023, pp. 412–423, https://doi.org/10.1002/hipo.23515.

Traxler, Larissa, et al. “Warburg-like metabolic transformation underlies neuronal degeneration in sporadic alzheimer’s disease.” Cell Metabolism, vol. 34, no. 9, Sept. 2022, https://doi.org/10.1016/j.cmet.2022.07.014.